diff --git a/freqtrade/freqtradebot.py b/freqtrade/freqtradebot.py
index 7ae87e807..32fbde562 100644
--- a/freqtrade/freqtradebot.py
+++ b/freqtrade/freqtradebot.py
@@ -54,8 +54,11 @@ class FreqtradeBot:
         # Init objects
         self.config = config
 
-        self._sell_rate_cache = TTLCache(maxsize=100, ttl=5)
-        self._buy_rate_cache = TTLCache(maxsize=100, ttl=5)
+        _process_throttle_secs = self.config['internals'].get('process_throttle_secs',
+                                                              constants.PROCESS_THROTTLE_SECS)
+        # Use 3x process_throttle_secs for caching to avoid delays in RPC methods.
+        self._sell_rate_cache = TTLCache(maxsize=100, ttl=_process_throttle_secs * 3)
+        self._buy_rate_cache = TTLCache(maxsize=100, ttl=_process_throttle_secs * 3)
 
         self.strategy: IStrategy = StrategyResolver.load_strategy(self.config)
 
diff --git a/tests/conftest.py b/tests/conftest.py
index d95475b8c..5c2e3e8e9 100644
--- a/tests/conftest.py
+++ b/tests/conftest.py
@@ -304,7 +304,8 @@ def default_conf(testdatadir):
         "user_data_dir": Path("user_data"),
         "verbosity": 3,
         "strategy_path": str(Path(__file__).parent / "strategy" / "strats"),
-        "strategy": "DefaultStrategy"
+        "strategy": "DefaultStrategy",
+        "internals": {},
     }
     return configuration