diff --git a/freqtrade/freqtradebot.py b/freqtrade/freqtradebot.py
index 101a9fc6c..f03fcf5b1 100644
--- a/freqtrade/freqtradebot.py
+++ b/freqtrade/freqtradebot.py
@@ -922,7 +922,9 @@ class FreqtradeBot(LoggingMixin):
         :param order: Current on exchange stoploss order
         :return: None
         """
-        if self.exchange.stoploss_adjust(trade.stop_loss, order):
+        stoploss_norm = self.exchange.price_to_precision(trade.pair, trade.stop_loss)
+
+        if self.exchange.stoploss_adjust(stoploss_norm, order):
             # we check if the update is necessary
             update_beat = self.strategy.order_types.get('stoploss_on_exchange_interval', 60)
             if (datetime.utcnow() - trade.stoploss_last_update).total_seconds() >= update_beat:
diff --git a/tests/test_freqtradebot.py b/tests/test_freqtradebot.py
index b52679f46..b22adb871 100644
--- a/tests/test_freqtradebot.py
+++ b/tests/test_freqtradebot.py
@@ -1359,6 +1359,32 @@ def test_handle_stoploss_on_exchange_trailing_error(
     assert log_has_re(r"Could not create trailing stoploss order for pair ETH/USDT\..*", caplog)
 
 
+def test_stoploss_on_exchange_price_rounding(
+        mocker, default_conf_usdt, fee, open_trade_usdt) -> None:
+    patch_RPCManager(mocker)
+    mocker.patch.multiple(
+        'freqtrade.exchange.Exchange',
+        get_fee=fee,
+    )
+    price_mock = MagicMock(side_effect=lambda p, s: int(s))
+    stoploss_mock = MagicMock(return_value={'id': '13434334'})
+    adjust_mock = MagicMock(return_value=False)
+    mocker.patch.multiple(
+        'freqtrade.exchange.Binance',
+        stoploss=stoploss_mock,
+        stoploss_adjust=adjust_mock,
+        price_to_precision=price_mock,
+    )
+    freqtrade = get_patched_freqtradebot(mocker, default_conf_usdt)
+    open_trade_usdt.stoploss_order_id = '13434334'
+    open_trade_usdt.stop_loss = 222.55
+
+    freqtrade.handle_trailing_stoploss_on_exchange(open_trade_usdt, {})
+    assert price_mock.call_count == 1
+    assert adjust_mock.call_count == 1
+    assert adjust_mock.call_args_list[0][0][0] == 222
+
+
 @pytest.mark.usefixtures("init_persistence")
 def test_handle_stoploss_on_exchange_custom_stop(
         mocker, default_conf_usdt, fee, limit_buy_order_usdt, limit_sell_order_usdt) -> None: