diff --git a/freqtrade/persistence/models.py b/freqtrade/persistence/models.py
index eee07e61c..2315c0acc 100644
--- a/freqtrade/persistence/models.py
+++ b/freqtrade/persistence/models.py
@@ -2,7 +2,9 @@
 This module contains the class to persist trades into SQLite
 """
 import logging
-from typing import Any, Dict
+import threading
+from contextvars import ContextVar
+from typing import Any, Dict, Final, Optional
 
 from sqlalchemy import create_engine, inspect
 from sqlalchemy.exc import NoSuchModuleError
@@ -19,6 +21,22 @@ from freqtrade.persistence.trade_model import Order, Trade
 logger = logging.getLogger(__name__)
 
 
+REQUEST_ID_CTX_KEY: Final[str] = 'request_id'
+_request_id_ctx_var: ContextVar[Optional[str]] = ContextVar(REQUEST_ID_CTX_KEY, default=None)
+
+
+def get_request_or_thread_id() -> Optional[str]:
+    """
+    Helper method to get either async context (for fastapi requests), or thread id
+    """
+    id = _request_id_ctx_var.get()
+    if id is None:
+        # when not in request context - use thread id
+        id = str(threading.current_thread().ident)
+
+    return id
+
+
 _SQL_DOCS_URL = 'http://docs.sqlalchemy.org/en/latest/core/engines.html#database-urls'
 
 
@@ -53,8 +71,9 @@ def init_db(db_url: str) -> None:
 
     # https://docs.sqlalchemy.org/en/13/orm/contextual.html#thread-local-scope
     # Scoped sessions proxy requests to the appropriate thread-local session.
-    # We should use the scoped_session object - not a seperately initialized version
-    Trade.session = scoped_session(sessionmaker(bind=engine, autoflush=False))
+    # Since we also use fastAPI, we need to make it aware of the request id, too
+    Trade.session = scoped_session(sessionmaker(
+        bind=engine, autoflush=False), scopefunc=get_request_or_thread_id)
     Order.session = Trade.session
     PairLock.session = Trade.session
 
diff --git a/freqtrade/rpc/api_server/deps.py b/freqtrade/rpc/api_server/deps.py
index aed97367b..eb41d728d 100644
--- a/freqtrade/rpc/api_server/deps.py
+++ b/freqtrade/rpc/api_server/deps.py
@@ -1,9 +1,11 @@
 from typing import Any, Dict, Iterator, Optional
+from uuid import uuid4
 
 from fastapi import Depends
 
 from freqtrade.enums import RunMode
 from freqtrade.persistence import Trade
+from freqtrade.persistence.models import _request_id_ctx_var
 from freqtrade.rpc.rpc import RPC, RPCException
 
 from .webserver import ApiServer
@@ -15,12 +17,19 @@ def get_rpc_optional() -> Optional[RPC]:
     return None
 
 
-def get_rpc() -> Optional[Iterator[RPC]]:
+async def get_rpc() -> Optional[Iterator[RPC]]:
+
     _rpc = get_rpc_optional()
     if _rpc:
+        request_id = str(uuid4())
+        ctx_token = _request_id_ctx_var.set(request_id)
         Trade.rollback()
-        yield _rpc
-        Trade.rollback()
+        try:
+            yield _rpc
+        finally:
+            Trade.session.remove()
+            _request_id_ctx_var.reset(ctx_token)
+
     else:
         raise RPCException('Bot is not in the correct state')
 
diff --git a/tests/rpc/test_rpc_telegram.py b/tests/rpc/test_rpc_telegram.py
index b1859f581..521e3b66d 100644
--- a/tests/rpc/test_rpc_telegram.py
+++ b/tests/rpc/test_rpc_telegram.py
@@ -674,8 +674,9 @@ def test_monthly_handle(default_conf_usdt, update, ticker, fee, mocker, time_mac
     assert str('Monthly Profit over the last 6 months</b>:') in msg_mock.call_args_list[0][0][0]
 
 
-def test_profit_handle(default_conf_usdt, update, ticker_usdt, ticker_sell_up, fee,
-                       limit_sell_order_usdt, mocker) -> None:
+def test_telegram_profit_handle(
+        default_conf_usdt, update, ticker_usdt, ticker_sell_up, fee,
+        limit_sell_order_usdt, mocker) -> None:
     mocker.patch('freqtrade.rpc.rpc.CryptoToFiatConverter._find_price', return_value=1.1)
     mocker.patch.multiple(
         EXMS,
@@ -710,6 +711,7 @@ def test_profit_handle(default_conf_usdt, update, ticker_usdt, ticker_sell_up, f
     # Update the ticker with a market going up
     mocker.patch(f'{EXMS}.fetch_ticker', ticker_sell_up)
     # Simulate fulfilled LIMIT_SELL order for trade
+    trade = Trade.session.scalars(select(Trade)).first()
     oobj = Order.parse_from_ccxt_object(
         limit_sell_order_usdt, limit_sell_order_usdt['symbol'], 'sell')
     trade.orders.append(oobj)