diff --git a/freqtrade/exchange/exchange.py b/freqtrade/exchange/exchange.py
index 799ee2c37..f6b722c9a 100644
--- a/freqtrade/exchange/exchange.py
+++ b/freqtrade/exchange/exchange.py
@@ -332,7 +332,8 @@ class Exchange:
                 logger.warning(f"Pair {pair} is restricted for some users on this exchange."
                                f"Please check if you are impacted by this restriction "
                                f"on the exchange and eventually remove {pair} from your whitelist.")
-            if not self.get_pair_quote_currency(pair) == self._config['stake_currency']:
+            if (self._config['stake_currency'] and
+                    not self.get_pair_quote_currency(pair) == self._config['stake_currency']):
                 invalid_pairs.append(pair)
         if invalid_pairs:
             raise OperationalException(