diff --git a/freqtrade/main.py b/freqtrade/main.py
index 754c536d0..0a46747ea 100755
--- a/freqtrade/main.py
+++ b/freqtrade/main.py
@@ -7,6 +7,8 @@ import logging
 import sys
 from typing import Any, List
 
+from freqtrade.util.gc_setup import gc_set_threshold
+
 
 # check min. python version
 if sys.version_info < (3, 8):  # pragma: no cover
@@ -36,6 +38,7 @@ def main(sysargv: List[str] = None) -> None:
         # Call subcommand.
         if 'func' in args:
             logger.info(f'freqtrade {__version__}')
+            gc_set_threshold()
             return_code = args['func'](args)
         else:
             # No subcommand was issued.
diff --git a/freqtrade/util/gc_setup.py b/freqtrade/util/gc_setup.py
new file mode 100644
index 000000000..a3532cbab
--- /dev/null
+++ b/freqtrade/util/gc_setup.py
@@ -0,0 +1,18 @@
+import gc
+import logging
+import platform
+
+
+logger = logging.getLogger(__name__)
+
+
+def gc_set_threshold():
+    """
+    Reduce number of GC runs to improve performance (explanation video)
+    https://www.youtube.com/watch?v=p4Sn6UcFTOU
+
+    """
+    if platform.python_implementation() == "CPython":
+        # allocs, g1, g2 = gc.get_threshold()
+        gc.set_threshold(50_000, 500, 1000)
+        logger.debug("Adjusting python allocations to reduce GC runs")